Irvine, CA (PRWEB)October 06, 2015: Bioniz, a biopharmaceutical company leading the discovery and development of first-in-class multiple-cytokine inhibitory therapeutics to address immunoinflammatory diseases and cancer immune-therapy, announced today its first two scientific publications in the prestigious peer-reviewed journals JBC and PNAS.
“These publications validate how Bioniz’s novel technology effectively selects and targets biologically redundant cytokines, an unprecedented functionality, which we believe will lead to the creation of a new and major class of drugs that comprehensively address the multiple drivers characteristic of immune system diseases,” said Nazli Azimi, CEO of Bioniz and co-inventor of the technology. “The issue of cytokine redundancy has been an obstacle to the development of effective anti-cytokine therapies. The current therapeutic approaches have been limited either to single monoclonal antibody (MAB) therapies against individual cytokines or to the use of JAK inhibitors that too broadly and non-exclusively block the downstream signaling components that follow cytokine activation. Humira, the monoclonal antibody set to eclipse Lipitor as the largest drug of all time, exemplifies the vast market potential of cytokine modulation. Even though Humira targets only one cytokine and is not highly specific to many of the disease states that have adopted it, it has still shown tremendous success for patients and created incredible market value. We hope to contribute such value many fold.”
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