MELBOURNE, Australia and NANTES, France, Jan. 18, 2017 (GLOBE NEWSWIRE) -- Telix Pharmaceuticals Limited (“Telix”) is pleased to announce the completion of a product collaboration and purchase option agreement with Atlab Pharma SAS (“Atlab”). Under the terms of the agreement, Telix will finance the manufacturing and clinical development of the huJ591 monoclonal antibody (mAb) radiolabelled with 177Lu (Lutetium) and 211At (Astatine), both promising “theranostic” products for the treatment of metastatic prostate cancer. The huJ591 mAb was originally developed by Dr. Neil Bander at the Weill Cornell Graduate School of Medical Sciences (New York, NY) and targets Prostate-Specific Membrane Antigen (PSMA), a well-validated target in prostate cancer.
The parties will collaborate to manufacture clinical material and work together to execute a multi-centre Phase IIb trial for the treatment of men with metastatic prostate cancer, with and without end-stage chemotherapy (standard care). In financing development, Telix also obtains an exclusive option to acquire Atlab under pre-agreed terms. The financial terms of the option exercise are not publicly disclosed at this time.
CEO Chris Behrenbruch stated, “PSMA targeting radiopharmaceuticals have shown great promise in both the diagnostic and therapeutic setting, dramatically increasing the interest in targeted radionuclide therapy by mainstream biopharma. The 177Lu-huJ591 program is the most clinically advanced PSMA program and has extensive patient experience, including in conjunction with anti-androgens and chemotherapy. We are very pleased to be working with Atlab to add this very promising program to Telix’s development pipeline.”
Read more: https://globenewswire.com/news-release/2017/01/18/909143/0/en/Telix-Pharmaceuticals-and-Atlab-Pharma-Conclude-Therapeutic-Product-Development-Agreement-for-Prostate-Cancer.html