BPS 2017


Production and Use of Collagen Mimetic Peptides for Therapeutic and Diagnostic Applications

Brian Del Buono

Vice President, Stuart Therapeutics

ABSTRACT

Stuart Therapeutics (formerly known as Sustain Scientific) has developed a technology that offers an innovative approach to targeting and delivery of a variety of therapeutic and diagnostic agents. This technology builds upon proprietary structures for collagen mimetic peptides (CMPs), which not only mimic human collagen in its structure, chemistry and behavior, but which also have been shown to intrinsically promote tissue healing, speeding the healing process. Importantly, the CMPs also can deliver small and large molecule therapeutics, biologics and diagnostic agents in a targeted fashion. Using Stuart Therapeutics’ CMP-based approach, the bioavailability of linked drugs and/or biologics can be modulated, creating numerous possibilities for targeted and sustained/timed delivery of medications, at more precise and effective dosages, to a specific area of damage or disease condition, potentially reducing the magnitude of the clinical problem of poor patient compliance in medication administration. The flexibility of Stuart Therapeutics’ CMP-based technology thus offers a new and unique way to control the dosing, efficacy, and potentially the adverse side effects of many therapeutic and diagnostic agents already in use, and to improve the prospects of emerging therapeutic and diagnostic compounds. Stuart Therapeutics is exploring the use of this technology in the treatment and diagnosis of a variety of human and animal diseases and disorders, including those afflicting the eye, skin, and other organs and organ systems, as well as certain types of cancers.

BIO

Dr. Del Buono has over 30 years of multinational R&D, legal and regulatory experience in technology development and licensing, with an emphasis on both branded and generic pharmaceuticals, biologics and medical devices. He has worked extensively in intellectual property, regulatory affairs, strategic business development, mergers and acquisitions and technology licensing. He also has substantial experience in biotech/pharma R&D innovation and management, and has had key responsibilities in large merger integration efforts. Prior to joining Sustain Dr. Del Buono was Sr. VP, Chief Legal Officer & Corporate Secretary for The Sun Products Corporation, was a partner at a Washington, DC intellectual property law firm, and was manager of New Products Development for a division of Becton Dickinson. He holds a Ph.D. in Microbiology/Biochemistry from The Pennsylvania State University and a J.D., cum laude, from Georgetown University Law Center, and was a postdoctoral fellow in Biochemistry and Hematology/Oncology at Boston University School of Medicine.

Information for BPS Presenters

The Boulder Peptide Foundation was established to further the science and knowledge of peptide technology to develop novel therapeutics, biomaterials, medical diagnostics and other beneficial uses for mankind. As part of this goal we run several programs to support career advancement, seminars and educational events. Join us on our mission to expand the applications of peptide science.

Information for BPS Presenters

The purpose of the Boulder Peptide Symposium is to encourage sharing of information related to peptide therapeutic development with an emphasis on the technical, scientific and regulatory aspects of the pharmaceutical development. Presentations that demonstrate original thinking or share experiences from case studies in product development shall receive priority over others.

The Boulder Peptide Symposium offers multiple opportunities for participants to present.

Oral Presentations in Scientific Sessions

The session topics for Scientific Program are Peptides in the Clinic, Drug Delivery, Chemistry of Complex Peptides, Spotlight on Discovery, and Peptide Showcase. Abstracts may be submitted via the Apply to Present page on the website. Submissions will be reviewed by the Scientific Advisory Board on a monthly basis and the speaker will be notified of a decision.

Presentation length: Format is 25-30 minutes slide presentation with 5-10 minutes for Q&A, with the exception of Peptide Showcase talks which are 10 minute slide presentations with 5 minutes for Q&A. Please confirm with your session chair to confirm the exact presentation length.

Invited Speakers: Speakers are requested to supply their presentation details 30 days after receiving an invitation to present.

Program Book Deadline: Final abstract and title must be provided no later than September 1st. No changes to the program are possible after this date.

Presentation Format: Oral presenters please provide your presentation slides to the A/V table on the day of your presentation.

Lodging: All speakers are requested to reserve their own room. Discount rates at the conference hotel are available until August 16th.

Registration: All speakers, excluding sponsored presentation speakers, receive a complimentary registration upon approval of the abstract.

Peptide Showcase Description

The Peptide Showcase is an opportunity for an individual or company to “showcase” new ideas, technology and pipeline assets. Priority shall be given to presentations from biotech and startup companies. Service providers and vendors are not eligible. Speakers in the session receive a complimentary event registration.

Posters

Posters can be presented on any topic relevant to peptides including original research, innovative products and technologies.

Eligibility- Any attendee (from academia, industry, biotech or vendor/sponsor) can present a poster. The presentation must contain original scientific thinking. To submit a poster go to the Submit a Poster link from the meeting menu. All submissions are reviewed on a rolling basis and will be notified of approval. September 1st is the last day to submit a poster abstract. Approved posters are published on the BPF website.

A 30 ” x 40″ board shall be provided with thumb tacks. Board will be on an easel and can be rotated for either landscape or portrait formats. Once you apply for a poster, you will get email confirmation that your poster was accepted. The poster session and number assignments will be emailed one week before the Symposium.

Poster boards shall be available for display from 8am to 8pm the day of your assigned poster session. See the program agenda for the poster session schedule.

Public Release

Every presentation at the Boulder Peptide Symposium is automatically recorded. Speakers are required to give consent for sharing of the presentation video with the peptide community.