Professor of Chemistry, Wayne State University
Strategies for the Synthesis of Topologically Complex Peptide Natural Products
Research in the Stockdill group is focused on the design of elegant and efficient strategies for the synthesis of neuroactive molecules ranging from complex alkaloids to disulfide-linked mini-proteins and for the detection of neurotransmitters. In the course of these efforts, we explore chemical reactivity and develop new reaction methods. This seminar will highlight our recent progress toward the synthesis of topologically complex polypeptide natural products such as alpha-conotoxins and macrocyclic peptides.
Jenn completed her undergraduate studies at Virginia Tech in Blacksburg, VA, where she graduated magna cum laude with a BS in Chemistry in 2003. From there, she moved to Pasadena, CA, where she completed a PhD in Chemistry in 2009 under the guidance of Prof. Brian M. Stoltz at Caltech. She then joined the group of Prof. Samuel J. Danishefsky at the Sloan-Kettering Institute at MSKCC. She joined the faculty of the Department of Chemistry at Wayne State University as an Assistant Professor in 2012 and was promoted to Associate Professor with tenure in 2019. Jenn’s research program focuses on the design of novel strategies and methods for the synthesis of neuroactive and potentially neuroactive small molecules and peptides.