Three approaches for the chemical ligation of peptides to cotton fibers are described and compared. This investigation was encouraged by the need to create peptide-decorated natural textiles, furnished with useful properties (e.g. antimicrobial activity). IR absorption spectroscopy is proved to be an easy and fast method to check the covalent anchorage of a peptide to cotton, whereas for a quantitative determination, a UV absorption method was employed. We also analyzed the usefulness of electron paramagnetic resonance spectroscopy to characterize our peptide-cotton conjugates. Copyright © 2014 European Peptide Society and John Wiley & Sons, Ltd.
In this work, three approaches for the chemical ligation of peptides and dendrimers to cotton fibers are described and compared. Characterization of the peptide bound to the cotton was achieved by means of IR absorption, UV, and electron paramagnetic resonance spectroscopies.