Source: Soligenix, Inc. & reported by http://www.prnewswire.com/
Princeton, N. J., Sept. 6, 2016 /PRNewswire/ -- Soligenix, Inc. (OTCQB: SNGX) (Soligenix or the Company), a late-stage biopharmaceutical company focused on developing and commercializing products to treat rare diseases where there is an unmet medical need, announced today that the United States (US) Patent Office granted the patent entitled "Peptides for Treating and Preventing Immune-Related Disorders, Including Treating and Preventing Infection by Modulating Innate Immunity." The newly issued patent claims composition of matter of analogs of dusquetide (research name: SGX94), the Company's lead development compound. Dusquetide recently demonstrated positive preliminary results in a Phase 2 clinical trial for the treatment of oral mucositis in head and neck cancer patients. The recently issued patent broadens the protection around dusquetide and provides further protection for the underlying innate defense regulator (IDR) technology platform. Similar claims have been granted and/or are being pursued in jurisdictions worldwide.
IDRs are first-in-class small peptides with a novel mechanism of action. IDRs function by modulating the response of the innate immune system at a key convergence point in the intracellular signaling pathways. The innate immune system is a non-specific system which responds to a variety of insults, including infections and tissue damage. Because IDRs act by modulating the response of the innate immune system, they are agnostic as to either the cause of tissue damage (e.g., chemotherapy, radiation or trauma) or infection (e.g., antibiotic sensitive or antibiotic resistant infections). A summary of the IDR technology can be found in the following audio presentation entitled, "Dusquetide: Innate Defense Regulation as a Novel Approach to Antibiotic-Resistant Infection": https://www.youtube.com/watch?v=ef0-wQod-2E&feature=youtu.be
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