BPS 2018 Proceedings
Young Investigator Keynote address

Jevgenij Raskatov
Assistant Professor in Biochemistry and Chemistry
University California Santa Cruz
Chirality, Alzheimer’s Disease, and Amyloid Beta
Peptide Showcase
Brief 15 minute presentations from companies developing peptide therapeutics and related technologies. This rapid and compressed format is designed for quick introduction between symposium participants to new technologies, and companies. Each presentation is structured to highlight the value of the technology or therapeutic being offered and the business strategy.

Melvin Klegerman
Professor
University of Texas Health Science Center at Houston
A Fibrin-Binding Peptide for Targeting Drug-Loaded Liposomes to Atherosclerotic Plaques

Michael Coe
Chief Scientific Officer
Phoreus Biotechnology, Inc.
Redefining Bio-Delivery with Peptide Nanotechnology

Jennifer Neff
Jennifer
Allvivo Vascular
Engineered antimicrobial peptides and their application to prevent medical device associated infections

Amit Michaeli
CTO
Pepticom Ltd.
Ab initio Computational Peptide Discovery: Concepts and Examples.

Mark McLaughlin
Mark
Modulation Therapeutics Inc
225Ac-DOTA-MC1RL as a novel therapy for metastatic uveal melanoma

David Guay
David
Feldan Therapeutics
Novel peptide technology to deliver proteins and CRISPR ribonucleoproteins in cells

Richard Liggins
CSO
Zucara Therapeutics
ZT-01, a First in Class Drug to Prevent Hypoglycemia in Type 1 Diabetes

Martin Handfield
Senior VP, Research
Oragenics
Lantibiotics for the Treatment of Clostridium difficile Associated Disease

Mark Edelsward
Director of Business Development
PharmaIN Corp.
PharmaIN makes Peptides better! PharmaIN leverages proprietary platforms for API enhancement and delivery

Meredith Hay
Founder and CSO
ProNeurogen
Glycoslyated Angiotensin 1-7 as novel treatment for cognitive impairment

Laurie Broadwater
Head of Analytical Chemistry
Thermalin Inc
Reducing the Burden of Insulin Therapy

Dwight Morrow
VP Preclinical Development
Magenta Therapeutics
Rapid and Robust Mobilization of Hematopoietic Stem Cells With MGTA-145: A Truncated Protein Variant of the Chemokine CXCL2

Carola Leuschner
Consultant for Intendet Services
Intendet Services LLC
Novel peptides for immune stimulation and synergy with checkpoint inhibitors

Maria Soloveychik
CEO
SyntheX
Cell based production and selection of PPI-modulating peptides and applications in oncology.

Philip Kim
Associate Professor
University of Toronto
Method to generate highly stable D-amino acid analogs of bioactive helical peptides using a mirror image of the entire PDB
Research Showcase
Brief 15 minute presentations of applied research from the academic labs.

Gerardo Byk
Gerardo
Bar Ilan University
Novel peptide isolated from Middle Asian Tortoise spleen extract induces repopulation of mice bone marrow after irradiation.

Jack Henkin
Research Professor, Chemistry, Center for Developmental Therapuetics
Northwestern University
Peptides enabling extended intravitreal drug delivery as nano-particle conjugates

Tambet Teesalu
Professor
University of Tartu, Estonia
Tumor penetrating peptides: discovery and clinical development
Peptides in the Clinic
Updates on clinical development of peptide therapeutics.

Dieter Willbold
Dieter
Forschungszentrum Jülich
PD, PK and target engagement of the orally available all-D-enantiomeric peptide PRI-002 developed for causal therapy of Alzheimer’s disease using direct Aβ oligomer elimination as MoA

Bernhard Fischer
CEO
APEPTICO
Design and clinical application of SOLNATIDE, a new peptide for treatment of critical pulmonary dysfunctions

Nazli Azimi
Founder, President and CEO
Bioniz Therapeutics
Characterization of a Novel, Multi-Cytokine Inhibitor, BNZ-1, for the Treatment of T-cell Malignancies and Alopecia Areata

Emmanuel Dauty
Head of the Physical Chemistry Department
Adocia Inc
Overcoming Formulation and Administration Challenges of Biomolecules BioChaperone® Technology: a Platform to Improve Solubility and Stability of Proteins and Peptides

Ashok Bhandari
Ashok
Protagonist Therapeutics
PTG-300, AN HEPCIDIN MIMETIC PEPTIDE FOR TREATMENT OF INEFFECTIVE ERYTHROPOIESIS AND CHRONIC ANEMIA IN HEMOGLOBINOPATHY DISEASES

Steven Prestrelski
Chief Scientific Officer
Xeris Pharmaceuticals, Inc.
XeriSol Formulation Technology for Stable Peptide Injectables

Andy Parker
CSO
Zealand Pharma
Dasiglucagon, a novel ready-to-use glucagon analog in development for treatment of severe hypoglycaemia
Drug Delivery
Novel approaches to peptide drug delivery including devices, molecular engineering, conjugation, and formulation technologies

Harald Rau
Chief Scientific Officer
Ascendis Pharma
TransCon technology for sustained delivery of proteins, peptides, and small molecules

Becky Nofsinger
Becky
Merck
Novel Approaches for Evaluating and Enhancing Oral Absorption of Peptides

Kennett Sprogøe
Senior Vice President, Product Innovation
Ascendis Pharma
TransCon technology for sustained delivery of proteins, peptides, and small molecules

Ernest Giralt
Professor
IRB Barcelona
Peptides for molecular recognition and brain delivery

Sheauyu Hsu
Sheauyu Teddy
Adepthera
Development of a novel peptide-centric sustained release system
Advances in Chemistry

Erika Olson
Postdoctoral Researcher
Harvard Medical School
Rational Development of a Peptide Antagonist for EphA4, a Cell-Surface Receptor Linked to Neurodegeneration

James Nowick
Professor and Department Chair
University of California, Irvine, Department of Chemistry
Unlocking the Mysteries of Amyloid Diseases with Macrocyclic β-Sheet Peptides

Lin Yan
Principal Scientist
Merck & Co., Inc.
Synthesis and Characterization of Glucose Responsive Insulins

Phil Dawson
Professor
TSRI
Peptide macrocycle conformational engineering using a rigid, linear linker

Carrie Haskell-Luevano
Carrie
University of Minnesota
Peptide GPCR Dimers: opportunities for drug design and chemical probe discovery

Megan Thielges
Megan
Indiana University
Site-Specific Infrared Spectroscopy of Conformational Heterogeneity in Proline-Rich Motif Recognition

Erika Olson
Postdoctoral Researcher
Harvard Medical School
Rational Development of a Peptide Antagonist for EphA4, a Cell-Surface Receptor Linked to Neurodegeneration

James Nowick
Professor and Department Chair
University of California, Irvine, Department of Chemistry
Unlocking the Mysteries of Amyloid Diseases with Macrocyclic β-Sheet Peptides

Lin Yan
Principal Scientist
Merck & Co., Inc.
Synthesis and Characterization of Glucose Responsive Insulins

Phil Dawson
Professor
TSRI
Peptide macrocycle conformational engineering using a rigid, linear linker

Carrie Haskell-Luevano
Carrie
University of Minnesota
Peptide GPCR Dimers: opportunities for drug design and chemical probe discovery

Megan Thielges
Megan
Indiana University
Site-Specific Infrared Spectroscopy of Conformational Heterogeneity in Proline-Rich Motif Recognition