- Amytrx expanding their bioactive peptide platform
- AMTX-100 has unique specificity to target leukocytes involved in the overactive immune response
- AmbioPharm providing peptide manufacturing support for Amytrx
- Amytrx looking to expand partnerships to advance new or complementary therapies
NASHVILLE, Tenn. & NORTH AUGUSTA, S.C.--(BUSINESS WIRE)--Amytrx Therapeutics, a mission-driven biopharmaceutical company dedicated to commercializing transformative and cutting-edge human anti-inflammatory peptides, has expanded their bioactive peptide platform beyond the original lead therapeutic molecule to include a multi-purpose drug delivery vehicle and imaging agent. In its recently completed Phase I/IIa clinical trial as part of an FDA-approved adaptive Phase I/II clinical protocol, AMTX-100 has shown great potential in rapidly improving outcomes for patients with the inflammatory skin disorder, atopic dermatitis (AD). A Phase IIb in adult subjects with mild to moderate AD is planned to start in 3Q 2022. Preclinical studies conducted for AMTX-100 to date allow for additional skin indications to start as Phase II trials. Amytrx is targeting additional studies in adolescent mild to moderate AD, psoriasis, lupus, rosacea, acne, shingles, herpes, and re-epithelialization/healing after chemical peels. Further, with its recent pre-clinical and clinical progress, Amytrx has identified new opportunities for other inflammatory and metabolic diseases with attractive out-licensing and collaborative opportunities using its proprietary AMTX-100 human peptide platform.
The advantages which AMTX-100 provides are twofold. The first is its unique specificity to target leukocytes involved in the overactive immune response and the second is its ability to cross cell membranes and enter the nucleus through natural mechanisms already utilized by cells. As such, the resulting peptide platform shows great promise in a wide range of therapeutic and delivery applications in inflammation, autoimmunity, and cancer. This comes on the heels of Amytrx Therapeutics’ most recent fundraising for the last tranche of its Series A round totaling $18 million to address novel human peptide interventions for AD and other skin disorders.